We have developed a proprietary sustained release carrier, SB Gel, which can be easily loaded with antimicrobials and applied as an injectable liquid. After injection, SB Gel conforms to surgical site surfaces and thickens into a semi-solid material. It then releases its antimicrobial payload over multiple days, and subsequently dissolves and is excreted.
To our knowledge, SB Gel is the only drug delivery technology combining these required capabilities for biofilm infections:
- Sustained antimicrobial release, eradicating residual bacteria.
- Conformation with complex surgical site surfaces, protecting the entire site.
- Complete degradation within weeks, allowing normal postoperative healing.